Agent Skills Directory

Set up a new autoresearch experiment interactively. Collects domain, target file, eval command, metric, direction, and evaluator.

Designs and implements backend systems including REST APIs, microservices, database architectures, authentication flows, and security hardening. Use when the user asks to "design REST APIs", "optimize database queries", "implement authentication", "build microservices", "review backend code", "set up GraphQL", "handle database migrations", or "load test APIs". Covers Node.js/Express/Fastify development, PostgreSQL optimization, API security, and backend architecture patterns.

Review UI code for Web Interface Guidelines compliance. Use when asked to "review my UI", "check accessibility", "audit design", "review UX", or "check my site against best practices".

Memory health dashboard showing line counts, topic files, capacity, stale entries, and recommendations.

Data engineering skill for building scalable data pipelines, ETL/ELT systems, and data infrastructure. Expertise in Python, SQL, Spark, Airflow, dbt, Kafka, and modern data stack. Includes data modeling, pipeline orchestration, data quality, and DataOps. Use when designing data architectures, building data pipelines, optimizing data workflows, implementing data governance, or troubleshooting data issues.

Run nf-core bioinformatics pipelines (rnaseq, sarek, atacseq) on sequencing data. Use when analyzing RNA-seq, WGS/WES, or ATAC-seq data—either local FASTQs or public datasets from GEO/SRA. Triggers on nf-core, Nextflow, FASTQ analysis, variant calling, gene expression, differential expression, GEO reanalysis, GSE/GSM/SRR accessions, or samplesheet creation.

World-class senior data scientist skill specialising in statistical modeling, experiment design, causal inference, and predictive analytics. Covers A/B testing (sample sizing, two-proportion z-tests, Bonferroni correction), difference-in-differences, feature engineering pipelines (Scikit-learn, XGBoost), cross-validated model evaluation (AUC-ROC, AUC-PR, SHAP), and MLflow experiment tracking — using Python (NumPy, Pandas, Scikit-learn), R, and SQL. Use when designing or analysing controlled experiments, building and evaluating classification or regression models, performing causal analysis on observational data, engineering features for structured tabular datasets, or translating statistical findings into data-driven business decisions.

Deep learning for single-cell analysis using scvi-tools. This skill should be used when users need (1) data integration and batch correction with scVI/scANVI, (2) ATAC-seq analysis with PeakVI, (3) CITE-seq multi-modal analysis with totalVI, (4) multiome RNA+ATAC analysis with MultiVI, (5) spatial transcriptomics deconvolution with DestVI, (6) label transfer and reference mapping with scANVI/scArches, (7) RNA velocity with veloVI, or (8) any deep learning-based single-cell method. Triggers include mentions of scVI, scANVI, totalVI, PeakVI, MultiVI, DestVI, veloVI, sysVI, scArches, variational autoencoder, VAE, batch correction, data integration, multi-modal, CITE-seq, multiome, reference mapping, latent space.

Comprehensive DevOps skill for CI/CD, infrastructure automation, containerization, and cloud platforms (AWS, GCP, Azure). Includes pipeline setup, infrastructure as code, deployment automation, and monitoring. Use when setting up pipelines, deploying applications, managing infrastructure, implementing monitoring, or optimizing deployment processes.

ML engineering skill for productionizing models, building MLOps pipelines, and integrating LLMs. Covers model deployment, feature stores, drift monitoring, RAG systems, and cost optimization. Use when the user asks about deploying ML models to production, setting up MLOps infrastructure (MLflow, Kubeflow, Kubernetes, Docker), monitoring model performance or drift, building RAG pipelines, or integrating LLM APIs with retry logic and cost controls. Focused on production and operational concerns rather than model research or initial training.

This skill should be used when the user asks to "optimize prompts", "design prompt templates", "evaluate LLM outputs", "build agentic systems", "implement RAG", "create few-shot examples", "analyze token usage", or "design AI workflows". Use for prompt engineering patterns, LLM evaluation frameworks, agent architectures, and structured output design.

Database Designer - POWERFUL Tier Skill